Manchin Family Values

Heather Manchin Bresch, the CEO of Mylan, on CNBC.

“Ever since I’ve been in this position, and when I was governor, we made a point –we just didn’t get involved. It’s so convoluted, I don’t understand. To get into something you don’t understand and your daughter being in this type of industry – it was best I stayed away. My daughter is my daughter with unconditional love, and she’s the most amazing person that I know. She’s so compassionate and generous in how she’s always lived her life.”

—Senator Joe Manchin to Bloomberg News in September 2016. His daughter Heather Manchin Bresch, the CEO of Mylan, had raised the price of EpiPens by almost 500% since 2009.

EpiPens are life-saving devices for people who go into anaphylactic shock after exposure to certain substances —peanuts, the venom in a bee sting, latex and others. The medicine in an EpiPen costs pennies; it is epinephrine, a synthesized version of adrenaline, the hormone made by our bodies. The EpiPen has a patented spring-loaded injector that makes it unnecessary to draw medicine into a syringe prior to injection. (Time is of the essence when a person is going into anaphylactic shock.) Purchasers are reminded that epinephrine loses potency over time and EpiPens have to be purchased annually. The EpiPen two-pack sold by Mylan that cost a little over $100 in 2009 and would cost a little under $500 in 2016 thanks to Joe Manchin’s daughter.

The EpiPen is the product of US taxpayer-funded research conducted in the 1970s for the Pentagon —which wanted an auto-injector device for soldiers facing exposure to nerve gas— by a company called Survival Technology.  The rights to market a civilian version to prevent anaphylaxis were then sold and re-sold. Survival merged with Brunswick, which sold the rights to Dey, a subsidiary of Merck, which in 2007 sold the rights to Mylan, which made a production deal with King, a wholly-owned subsidiary of Pfizer.

After some superficial improvements (a stronger spring, clearer instructions) that supposedly justified raising prices, Mylan began its big marketing push in 2009. With almost 90% of the market, their key goal was to get every school in the US to keep EpiPens on hand. Children face the highest risk of a fatal response because many never been exposed to the substance they’re allergic to. Adults generally know what they’re allergic to and try to avoid exposure or carry the antidote.

As Governor of West Virginia, Joe Manchin had appointed his wife to the state Board of Education in 2007. By 2012 Gayle Conelly Manchin would be president of the National Association of State Boards of Education, an official-sounding-but-private outfit that lobbies state boards to adopt policies favored by Association members. In 2016 USA Today (a paper that doesn’t get enough credit for serious muckraking) reported that Mrs. Manchin had “spearheaded an unprecedented effort that encouraged states to require schools to purchase medical devices that fight life-threatening allergic reactions.

“The association’s move helped pave the way for Mylan Specialty, maker of EpiPens, to develop a near monopoly in school nurses’ offices. Eleven states drafted laws requiring epinephrine auto-injectors. Nearly every other state recommended schools stock them after what the White House called the ‘EpiPen Law’ in 2013 gave funding preference to those that did.”

It’s reassuring to know that none of this was ever discussed when the Manchins’ daughter Heather was in earshot. At Thanksgiving dinner it was all “Please pass the mashed potatoes, dad.”

Heather’s brilliant career was launched after Joe Manchin introduced her to the CEO of Mylan. Although her claim to have a Master’s Degree in Business Administration was exposed as a lie, her fast rise to the top was unimpeded. Heather had something better than a degree, she had real audacity. And so she quadrupled the price of a drug that several million US Americans must have on hand and buy every year. (Somebody ought to confirm that epinephrine degrades significantly in a year. It might be a pseudo-scientific marketing device like Dial Soap’s famous “Rinse and repeat.”)

Heather’s salary rose from $2.5 million in 2007 to $18.9 million in 2015. She was then 45 years old and would have become the poster child of Pharmaceutical Industry Greed had it not been for Martin Shkreli, who raised the price of the anti-parasitic drug Diapram from $13.50 to $750. Then the publicity-welcoming “pharma bro” won the auction for the world’s only copy of a hip-hop album by Wu-Tang Clan. Shkreli was sentenced to seven years and may still be doing time for securities fraud, but presumably, he got to enjoy “Once Upon a Time in Shaolin” before the 2-CD rarity was seized by the feds.

Heather is married to a corporate lawyer named Jeffrey Bresch whose firm represents, in addition to numerous Fortune 500 companies, the Pennsylvania Republican Party in its challenge to the validity of votes mailed in on Election Day in 2020. (But that’s another story). Heather retired at age 50 in 2020 after arranging Mylan’s merger with Upjohn. The first woman to head a Fortune 500 Pharmaceutical company, her accomplishments included Mylan’s acquisition of Abbott Laboratories and a transfer of corporate headquarters to the Netherlands, bringing the merged companies’ tax rate down from 24% to 21%. The moral of the story is: you don’t really need an MBA to be a successful corporate executive.

PS: In March 2021, President Biden appointed Gayle Conelly Manchin to co-chair the Appalachian Regional Commission, which disperses federal grants — a $163,000 per year sinecure.

Fred Gardner is the managing editor of O’Shaughnessy’s. He can be reached at